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. 2005 Jul 28;568(Pt 2):559–571. doi: 10.1113/jphysiol.2005.093328

Figure 3. Immunohistochemical localization of EpoR in the caudal brainstem.

Figure 3

A, an anatomical overview and the ubiquitous expression of EpoR. Nucleus tractus solitarii (nTS; red box) and pre-Bötzinger complex (preBötC; green box) areas are shown in higher magnification. B, the expression of EpoR in the preBötC area. The preBötC was visualized by immunohistochemistry of EpoR and NK1R in serial brainstem sections obtained from WT and Tg21 mice. In both WT and Tg21 mice EpoR and NK1R colocalized in the preBötC neurones. Abbreviations: 4V, 4th ventricle; nTS, nucleus tractus solitarii; PY, pyramidal decussation; A1C1 and A2C2, catecholaminergic areas in the medulla oblongata; preBötC, pre-Bötzinger complex; NA, nucleus ambiguus; SP5, spinal trigeminal tract.