Table 1.

Morphological characteristics of Rpe65^−/− and WT mice

	WT cyclic light	Rpe65−/− dark	Rpe65−/− cyclic light
Retinal thickness (μm)	143 ± 5	111 ± 4	118 ± 7
OS length (μm)	13.9 ± 0.5	8.0 ± 0.2	7.9 ± 0.8
Rows of nuclei	9.0 ± 0.2	7.7 ± 0.3	6.5 ± 0.2

Errors are s.e.m.s for three animals of each condition (see Methods). Calculated average of nuclei in outer nuclear layer (ONL), outer segment length (OS), and retinal thickness for 11-month-old WT and Rpe65^−/− mice. Animals were dark-reared from 2 months of age (dark) or raised in cyclic light. See Methods for description of the selection of retinal sections. The values for each animal were determined from 48 measurements per eye, 3 from each of 16 photographs (see Methods). Means ±s.e.m. are given for 3 animals per condition (i.e. 144 measurements in total).