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. 2001 Jan 30;98(3):1294–1299. doi: 10.1073/pnas.98.3.1294

Figure 4.

Figure 4

Effect of NS398 on the lesion produced by direct microinjection of NMDA into the cerebral cortex of C57BL/6J mice. (A) PGE2 concentration in the injured cortex, 3 h after NMDA injection, in mice receiving vehicle (n = 5) or NS398 (n = 5; *, P < 0.05 from vehicle). (B and C) Thionin-stained brain sections showing the lesion produced by NMDA (arrow) in mice receiving vehicle or NS398. (D) Effect of NS398 (n = 6) or vehicle (n = 7) on the volume of the lesion produced by NMDA (*, P < 0.05 from vehicle). (E) Effect of NS398 on the lesion area at different rostrocaudal levels from the anterior commissure.