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. 2006 Jun;17(6):2824–2838. doi: 10.1091/mbc.E05-11-1040

Table 3.

Morphology, budding pattern, and mating efficiency of cdc42 mutants

Amino acid 36 Viability Morphologya Axial bud site selectionb Mating efficiencyc
Val + I 89 ++
Ala + II 65 +
Leu + I nd ++
Ile + I nd ++
Met + I/II 75
Phe + II nd nd
Ser + I 70 ++
Thr + II/III nd +
Tyr + III nd ++
Trp + III 49
Gln + I nd +
Cys + I 89 ++
Lys + II 58 +
Arg + II 70 nd
His + II/III 22 +
Glu nd nd nd

a Wild-type morphology (I), elongated cells (II), and large cells (III).

b Percentage axial budding pattern (n = 100).

c Plate mating efficiency with an enfeebled tester; ++, wild-type efficiency; +, slightly defective; and −, strongly defective.