Table 2.
Lesions in sfc Alleles
| Allele | Lesion | Allele Strength | Lesion Site Relative to Protein Domains |
|---|---|---|---|
| sfc-1 | C460Y | Strong | ARF-GAP |
| sfc-2 | AG to AA, 3′ splice site intron 1 | Strong | BAR |
| sfc-3 | Deletion at codon 225a | Strong | Between BAR and PH |
| sfc-4 | Q209STOP | Strong | Between BAR and PH |
| sfc-5 | AG to AA, 3′ splice site intron 7 | Strong | BAR |
| sfc-6 | D459N | Intermediate | ARF-GAP |
| sfc-7 | C to T, intron 10 (160th nucleotide of a 335-nucleotide intron) | Weak | Between BAR and PH |
| sfc-9 | T-DNA insertion in intron 1 Salk_069166 | Strong | BAR |
a
Inserted amino acids: CRSTKDRWIERAGGVEMVLMDHRMEMAYKESVEALTKStop.