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The contacts stabilized as a result of Src kinase inhibition are cadherin dependent. Immunofluorescence images of cells stained with phalloidin-FITC are shown for HEKs in low Ca2+ (top left), high Ca2+ (top right), and low Ca2+ in the presence of the Src-inhibitory drug PD162531 (bottom panels) in the absence (left panel) and presence of a mixture of E- and P-cadherin-specific antibodies (right panel). Bars 100 μm.
