TABLE 7.
Device and pharmacologic considerations for therapy in the Brugada syndrome
| Devices |
| √ ICD—only established effective therapy |
| ? Pacemaker |
| ? Ablation or cryosurgery |
| Pharmacologic |
| X Amiodarone—does not protect102 |
| X β-Blockers—does not protect102 |
| √ β-Adrenergic agonists—Isoproterenol8,10 |
| √ Phosphodiesterase inhibitors—cilostazol70 |
| X Class IC antiarrhythmics—Flecainide, Propafenone—contraindicated |
| Class IA antiarrhythmics |
| X Procainamide, Disopyramide—contraindicated |
| √ Quinidine72,104,105,108 |
| ? Tedisamil |
| √ Ito Blockers—cardioselective and ion channel specific |