Analysis of covariance of 21-item Hamilton Rating Scale for Depression from the blind evaluator for weeks 4, 7, and 10. At week 10 the active treatments reduced symptoms significantly more than placebo (phenelzine sulfate [F1,103 = 9.30; P<.01] and cognitive therapy [F1,103 = 8.94; P<.01], where 36 patients were randomized to each group).