Table 2.
Unadjusted Mean ± SE Symptom Severity Scores Before Treatment Through Weeks 4, 7, and 10 (End Point Carried Over)*
| Cognitive Therapy (n = 36) | Phenelzine Sulfate (n = 36) | Pill Placebo (n = 36) | |
|---|---|---|---|
| 21-Item Hamilton Rating Scale for Depression | |||
| Pretreatment | 21.11 ± 0.75 | 20.03 ± 0.60 | 21.22 ± 0.59 |
| Week 0 | 18.36 ± 0.60 | 16.75 ± 0.48 | 17.42 ± 0.50 |
| Week 4 | 15.53 ± 1.15 | 12.64 ± 1.14 | 17.08 ± 0.98 |
| Week 7 | 11.75 ± 1.17 | 8.92 ± 1.13 | 15.03 ± 1.18 |
| Week 10 |
10.25 ± 1.35 |
8.64 ± 1.07 |
14.44 ± 1.26 |
| Beck Depression Inventory | |||
| Pretreatment | 27.58 ± 1.22 | 27.86 ± 1.30 | 28.42 ± 1.17 |
| Week 0 | 25.83 ± 1.19 | 24.86 ± 1.44 | 26.19 ± 1.39 |
| Week 4 | 16.39 ± 1.64 | 16.19 ± 1.56 | 21.33 ± 1.80 |
| Week 7 | 13.00 ± 1.52 | 11.06 ± 1.56 | 19.33 ± 2.02 |
| Week 10 |
11.72 ± 1.62 |
9.67 ± 1.56 |
18.94 ± 2.12 |
| Clinical Global Impression Scale | |||
| Pretreatment | 4.03 ± 0.09 | 4.06 ± 0.04 | 4.06 ± 0.07 |
| Week 0 | 4.03 ± 0.09 | 3.86 ± 0.09 | 3.92 ± 0.10 |
| Week 4 | 3.56 ± 0.23 | 3.36 ± 0.23 | 4.03 ± 0.17 |
| Week 7 | 3.00 ± 0.22 | 2.44 ± 0.24 | 3.64 ± 0.25 |
| Week 10 | 2.47 ± 0.29 | 2.28 ± 0.24 | 3.44 ± 0.27 |
*
Pretreatment scores occurred before treatment began. Randomization occurred at week 0.