Table 2.
Genes that showed significant alterations (q ≤ 5%) in brains of scrapie-infected mice at 104 dpi
Scan | Clone ID | Name | SAM Score(d) | q-value (%) | Ave. FC |
L | AI848245 | beta-2 microglobulin* | 2.0 | 4.2 | 1.3 |
L | AI836786 | complement component 1 q alpha* | 2.1 | 4.2 | 1.3 |
L | AI835314 | cyclin-dependent kinase 5, regulatory subunit (p35) | 1.9 | 4.2 | 1.3 |
L | AI851280 | docking protein 4 | 1.8 | 4.2 | 1.2 |
L | AI854785 | endogenous retrovirus, Intracisternal A particles | 1.8 | 4.2 | 1.2 |
L | SSHI-2f6 | endogenous retrovirus truncated gag | 1.8 | 4.2 | 1.4 |
L | AI841933 | eukaryotic translation initiation factor 3, subunit 2 (beta) | 1.8 | 4.2 | 1.2 |
L | AI836096 | glial fibrillary acidic protein | 3.7 | 4.2 | 1.9 |
L | AI854206 | hexosaminidase B* | 2.0 | 4.2 | 1.3 |
L | AI848012 | kinesin family member 3A | 1.9 | 4.2 | 1.3 |
L | AI842053 | lectin, galactoside-binding, soluble, 3 binding protein* | 1.9 | 4.2 | 1.2 |
L | AI849127 | unknown EST | 2.0 | 4.2 | 1.3 |
L | AI854905 | unknown EST | 1.9 | 4.2 | 1.3 |
L | AI853719 | unknown EST | 1.8 | 4.2 | 1.3 |
L | SSHII-1h12 | not sequenced | 1.8 | 4.2 | 1.2 |
L | AI840066 | Immunoglobulin superfamily, member 4B* | 1.9 | 4.2 | 1.3 |
L | AI849299 | Protein tyrosine phosphatase, receptor type Z, polypeptide 1 | 1.8 | 4.2 | 1.2 |
L | AI851594 | RIKEN cDNA 1300010M03 gene | 1.8 | 4.2 | 1.2 |
L | AI850724 | RIKEN cDNA 2400003C14 gene | 2.3 | 4.2 | 1.3 |
L | AI843193 | RIKEN cDNA E130114P18 gene | 2.2 | 4.2 | 1.3 |
L | AI840441 | secretogranin III* | 1.9 | 4.2 | 1.2 |
L | AI846048 | RIKEN cDNA 2900073H19 gene | 1.8 | 4.2 | 1.3 |
* Genes with an asterisk encode proteins that localize to extracellular space
Clone ID is GenBank # for BMAP clones. Clone IDs that begin with SSHI are from Rashmi Korke's mouse cDNA library
L stands for low scan
FC stands for fold change