Table 2.

Conditional probabilities that two core promoter elements are spaced in a synergistically-favorable manner, given that both elements are present

Core promoter element pairs	p(synergy | both elements present)		One-tailed significance of synergy	p(synergy | both elements present and conserved in mouse counterparts)		One-tailed significance of synergy
	Real sequences	Randomized sequences		Real sequences	Randomized sequences
TATA-MTE	0.75	0.57	2.3 × 10-17	0.72	0.45	2.3 × 10-17
BRE-Inr	0.54	0.46	4.0 × 10-5	0.45	0.31	7.2 × 10-8
TATA-Inr	0.68	0.69	0.67	0.67	0.60	0.01
BRE-DPE	0.43	0.42	0.46	0.32	0.24	0.10
Inr-DPE	0.48	0.47	0.20	0.42	0.33	0.00
MTE-DPE	0.45	0.49	0.98	0.33	0.24	0.00
Inr-MTE	0.53	0.46	1.9 × 10-8	0.44	0.34	3.9 × 10-17
BRE-TATA	0.45	0.38	0.08	0.46	0.08	0.00
BRE-MTE	0.31	0.27	0.00	0.2	0.12	5.4 × 10-7
TATA-DPE	0.5	0.45	0.11	0.45	0.22	0.00