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. Author manuscript; available in PMC: 2006 Jun 12.
Published in final edited form as: Neurosci Lett. 2005 Feb 16;381(1-2):42–46. doi: 10.1016/j.neulet.2005.01.080

Fig. 1.

Fig. 1.

CAPS responses in DRG neurons from normal and FIC cats. (A) Time course of CAPS response in a neuron from normal cat in response to CAPS alone (0.5 μM, control) and PDBu (0.5 μM) applied immediately after the onset of CAPS response. (B) Time course of CAPS response in a neuron from normal cat (normal, thin dotted lines, same trace as control in (A)) and a neuron from an FIC cat in response to CAPS alone (0.5 μM, FIC). (C) Modulation of CAPS (0.5 μM) response in a normal cat neuron by PDBu (0.5 μM) and α-naphthyl acid phosphate (αNACP, 5 μM) and after TRPV1 antagonist (5 μM). (D) Slow onset, slowly desensitizing response to CAPS (0.5 μM) in a neuron from a cat with FIC. PDBu (0.5 μM) applied after partial desensitization of CAPS response. TRPV1 antagonist inhibited the partially desensitized current.