Table 7.
Time in Hospital and Nonhematologic Grade 3 and 4 Toxicities Related to Lymphodepleting Chemotherapy and Cell Transfer
Patients |
||
---|---|---|
Characteristic | No. | % |
Days in hospital* | ||
6-10 | 6 | 17 |
11-15 | 18 | 51 |
16-20 | 4 | 11 |
21-25 | 7 | 20 |
pRBC transfusions | ||
0 | 2 | 6 |
1-5 | 18 | 51 |
6-10 | 13 | 37 |
11-15 | 2 | 6 |
Platelet transfusions | ||
0 | 6 | 17 |
1-5 | 21 | 60 |
6-10 | 5 | 14 |
11-15 | 2 | 6 |
16-20 | 1 | 3 |
Autoimmunity | ||
Uveitis | 5 | 14 |
Vitiligo | 13 | 37 |
Opportunistic infections | ||
Herpes zoster | 3 | 9 |
Pneumocystis pneumonia | 2 | 6 |
EBV-B-cell lymphoma | 1 | 3 |
RSV pneumonia | 1 | 3 |
Other | ||
Febrile neutropenia | 13 | 37 |
Intubated for dyspnea | 3 | 9 |
Cortical blindness | 1 | 3 |
Abbreviations: pRBC, peripheral red blood cells; EBV, Epstein-Barr virus; RSV, respiratory syncytial virus.
Measured from the day of cell administration to discharge.