Table 2.

Kinetic constants for the budding yeast model

Rate constants (min−1)
k′s,n2 = 0	k″s,n2 = 0.05	kd,n2 = 0.1
k′s,b2 = 0.002	k″s,b2 = 0.05
k′d,b2 = 0.01	k″d,b2 = 2	k‴d,b2 = 0.05
k′s,b5 = 0.006	k″s,b5 = 0.02	k′d,b5 = 0.1	k″d,b5 = 0.25
k′s,c1 = 0.02	k″s,c1 = 0.1	kd1,c1 = 0.01	kd2,c1 = 0.3
kas,b2 = kas,b5 = 50	kdi,b2 = kdi,b5 = 0.05
k′s,20 = 0.005	k″s,20 = 0.06	kd,20 = 0.08
ka,20 = 1	k′i,20 = 0.1	k″i,20 = 10
k′a,t1 = 0.04	k″a,t1 = 2	k′i,t1 = 0	k″i,t1 = 0.64
ks,ori = 2	ks,bud = 0.3	ks,spn = 0.08
kd,ori = kd,bud = kd,spn = 0.06		ka,sbf = ka,mcm = ka,swi = 1
k′i,sbf = 0.5	k″i,sbf = 6	k′i,swi = 0.3	k″i,swi = 0.2
ki,mcm = 0.15	μ = 0.005776
Characteristic concentrations (dimensionless)
[Cln3]max = 0.02	[Bck2]0 = 0.0027	[Hct1]T = 1
Jspn = 0.2	Jd2,c1 = 0.05
Ja,sbf = Ji,sbf = 0.01	Ja,mcm = Ji,mcm = 1	Ja,swi = Ji,swi = 0.1	Ja,t1 = Ji,t1 = 0.05
Kinase efficiencies (dimensionless)
ɛc1,n3 = 20	ɛc1,k2 = 2	ɛc1,b2 = 0.067	ɛc1,b5 = 1
ɛi,t1,n2 = 1	ɛi,t1,b2 = 1	ɛi,t1,b5 = 0.5
ɛori,b2 = 0.4	ɛbud,b5 = 1	ɛsbf,n3 = 75	ɛsbf,b5 = 0.5
Other parameters (dimensionless)
f = 0.433	Jn3 = 6	Dn3 = 1