1 |
wild type |
0.71 |
1.07 |
1.15 |
1.15 |
1.64 |
84 |
|
CT 146 min |
|
(daughter) |
|
(71′) |
(84′) |
(84′) |
(146′) |
|
|
(time of occurrence of event) |
2 |
cln1 cln2 cln3 |
0.71 |
2.47 |
[6.20] |
[6.48] |
[8.11] |
|
Dn3 = 0 |
Richardson, 1989, inviable |
|
|
|
|
|
|
|
|
k″s,n2 = 0 |
3 |
cln1 cln2 cln3 |
0.65 |
0.65 |
0.75 |
0.95 |
1.50 |
25 |
Dn3 = 20 |
Schwob, 1993, Fig. 2, SBF activated soon |
|
GAL-CLN3 |
|
|
|
|
|
|
k″s,n2 = 0 |
after galactose induction
|
4 |
cln1 cln2 cln3 |
0.34 |
0.34 |
0.39 |
0.35 |
0.79 |
25 |
Dn3 = 0 |
Cross, 1991, Fig. 4, GAL-CLN1 induces cln2 |
|
GAL-CLN2 |
|
|
|
|
|
|
k′s,n2 = 0.1 |
|
|
|
|
|
|
|
|
|
k″s,n2 = 0 |
5 |
cln1 cln2 cln3 |
2.81 |
2.83 |
4.96 |
5.15 |
6.52 |
98 |
Dn3 = k″s,n2 = 0 |
Epstein, 1992, viable |
|
2X CLB5 |
|
|
|
|
|
|
k′s,b5 = 0.012 |
|
|
|
|
|
|
|
|
k″s,b5 = 0.04 |
6 |
cln1 cln2 cln3 |
1.23 |
2.07 |
2.05 |
2.14 |
2.86 |
88 |
Dn3 = k″s,n2 = 0 |
Schwob, 1993, Fig. 6, viable |
|
GAL-CLB5 |
|
|
|
|
|
|
k′s,b5 = 0.1 |
|
|
|
|
|
|
|
|
k″s,b5 = 0 |
7 |
cln1 cln2 cln3 |
0.71 |
2.57 |
[5.49] |
[6.64] |
[7.38] |
|
Dn3 = k″s,n2 = 0 |
Amon, 1994, Fig. 8, G1 arrest |
|
GAL-CLB2 |
|
|
|
|
|
|
k′s,b2 = 0.1 |
We consider cells arrested in G1 if mass at |
|
|
|
|
|
|
|
|
k″s,b2 = 0 |
DNA replication exceeds 5 |
8 |
cln1 cln2 cln3 |
1.30 |
2.12 |
1.50 |
2.24 |
3.01 |
24 |
Dn3 = k″s,n2 = 0 |
Tyers, 1996, Fig. 2, viable but large |
|
sic1 |
|
(85′) |
(24′) |
(94′) |
(146′) |
|
k′s,c1 = 0 |
|
|
|
|
|
|
|
|
k″s,c1 = 0 |
9 |
cln1 cln2 cln3 |
0.71 |
2.48 |
4.62 |
5.03 |
No mit |
|
Dn3 = k″s,n2 = 0 |
Schwab, 1997, Fig. 3, M phase arrest |
|
hct1 |
|
|
|
|
|
|
k″d,b2 = 0.01 |
10 |
cln1 cln2 cln3 |
0.71 |
2.48 |
4.16 |
4.60 |
No mit |
|
Dn3 = k″s,n2 = 0 |
Irniger, 1997, Fig. 2, M phase arrest |
|
apc-ts |
|
|
|
|
|
|
k″d,b2 = 0.01 |
|
|
|
|
|
|
|
|
k‴d,b2 = 0 |
|
|
|
|
|
|
|
|
k″d,b5 = 0 |