FIGURE 1.

Nucleosome core modeling using DiSCO. The top figure shows the crystal structure of the nucleosome without the histone tail residues (nucleosome core). The bottom figure shows our model nucleosome core with discretized charges. The charges on the nucleosome core are deliberately shown smaller than their excluded volume for clarity, and they are color-coded according to their magnitude relative to the electronic charge (e), as shown in the color chart. The surface of the nucleosome core has been displaced inwards by 2 Å to allow visibility of the charges.