FIGURE 1.

Schematic representation of the four factors discussed in the text for the model of protein denaturation. The protein is represented as a sphere with uniformly distributed negative charge on its surface. The dark patches represent hydrophobic regions on the surface of the protein that result from acylations. The depictions of SDS molecules are wavy lines (dodecanoic chain) with negatively charged headgroups (sulfate group). V-shaped entities represent water molecules.