(A) Force-indentation curve of a membrane in the gel phase (DODAB) covering a pore with a radius of Rpore = 90 nm. 1 represents the solution calculated using the small gradient approximation, whereas 2 shows the exact solution. In both cases, the following parameters were used: Rtip = 20 nm, Rpore = 90 nm, σgel = 5.0 mN m−1, and κgel = 1.0·10−18 J. (B) The same parameters as in A, but this time for a DOTAP membrane, using the following parameters: Rtip = 20 nm, Rpore = 90 nm, σfluid = 1.0 mN m−1, and κfluid = 0.1·10−18 J.