TABLE 1.
In vitro activities of posaconazole, itraconazole, fluconazole, voriconazole, and amphotericin B against all fungi, molds, and yeasts tested
Antifungal agent | In vitro activity againsta:
|
||||||||
---|---|---|---|---|---|---|---|---|---|
All fungi
|
All molds
|
All yeasts
|
|||||||
n | MIC (μg/ml)
|
n | MIC (μg/ml)
|
n | MIC (μg/ml)
|
||||
50% | 90% | 50% | 90% | 50% | 90% | ||||
POS | 22,850 | 0.063 | 1.0 | 4,499 | 0.125 | 1.0 | 18,351 | 0.063 | 1.0 |
ITC | 18,877 | 0.125 | 1.0 | 3,204 | 0.5 | 4.0 | 15,673 | 0.125 | 1.0 |
FLC | 17,884 | 0.5 | 128.0 | 1,779 | 256.0 | 256.0 | 16,105 | 0.5 | 16.0 |
VRC | 9,598 | 0.031 | 0.5 | 1,826 | 0.25 | 2.0 | 7,772 | 0.031 | 0.5 |
AMB | 16,567 | 1.0 | 1.0 | 3,013 | 1.0 | 2.0 | 13,554 | 1.0 | 1.0 |
n is the number of MICs determined. 50% and 90%, MIC50 and MIC90, respectively.