TABLE 4.

Pharmacodynamic values determined for the five tested strains of S. aureus (n = 2)

Parameter and time point	Pharmacodynamic value for strain:
	ATCC 25923 (MIC = 0.1 μg/ml)	SA-1 (MIC = 0.5 μg/ml)	Sa2102 (MIC = 0.2 μg/ml)	Sa2667 (MIC = 0.5 μg/ml)	Sa2669 (MIC = 1.0 μg/ml)
Cmax/MIC
1 h	53.6	9.76	24.9	9.20	4.93
25 h	58.0	10.1	29.3	10.2	5.68
AUC0-24/MIC	306	61.2	153	61.2	30.6
Δlog CFU/ml
t1	−2.18	−1.22	−0.59	−0.49	−0.33
t24	−6.80	−1.80	0.04	−0.92	−0.43
t25	−6.80	−1.68	0.05	−1.43	−0.58
t48	−6.80	1.53	3.02	2.57	2.25
ABBC0-48 (h × log CFU/ml)	419