TABLE 3.
Comparative reactivities between the current Multispot study and OQ HIV-1 false-negative specimens
| Reactivity | Result for specimen type
|
|||
|---|---|---|---|---|
| TACC NHS, 2004-2005 (n = 248)
|
OQ FN, 2000a (n = 4)
|
|||
| No. reactive (%) | Mean ± SD | No. reactive (%) | Mean ± SDb | |
| Multispot reactivity | ||||
| Spot 1 | 248 (100) | 3.13 ± 0.33 | 4 (100) | 3.75 ± 0.5 |
| Spot 2 | 0 (0) | 0.0 ± 0.0 | 0 (0) | 0.0 ± 0.0 |
| Spot 3 | 248 (100) | 3.64 ± 0.68 | 4 (100) | 2.25 ± 0.96 |
| Spot 4 | 248 (100) | 3.94 ± 0.24 | 4 (100) | 2.00 ± 0.82 |
| Western blot reactivity | ||||
| p24 | 248 (100) | 1.94 ± 0.23 | 4 (100) | 1.00 ± 0.00 |
| gp41 | 246 (99.2) | 1.90 ± 0.32 | 4 (100) | 0.88 ± 0.25 |
| gp120 | 248 (100) | 1.93 ± 0.25 | 4 (100) | 1.25 ± 0.50 |
| gp160 | 248 (100) | 2.00 ± 0.00 | 4 (100) | 2.00 ± 0.00 |
| EIA reactivity for HIV-1 | 248 (100) | 4 (100) | ||
| No. (%) of specimens HIV-1 positivec | 248 (100) | 4 (100) | ||
a
OQ FN, OQ HIV-1 false-negative subjects (7).
b
For comparisons between OQ false negatives and TACC NHS semiquantitative Multispot and Western blot reactivity, P was <0.0001 for all comparisons except for spot 2 and gp160, where the P value was 1.000 (Mann-Whitney U).
c
HIV-1 positivity was determined by a comparison of EIA and WB results.