FIG. 5.

ELISA analysis of the antibody responses of P. falciparum-infected children to S. mansoni SmLRR. Plasma samples were obtained from the following two groups of Kenyan schoolchildren: children who were malaria and schistosomiasis negative and had low levels of anti-Pfs IgG3 and anti-SEA IgG4 (n = 20) (A) and children who were malaria positive and schistosomiasis negative and had detectable levels of anti-Pfs IgG3 but low levels of anti-SEA IgG4 (n = 20) (B). These samples were assayed for IgG1, IgG3, and IgG4 reactivity with Pfs, S. mansoni, SWA, and recombinant SmLRR. The results are expressed as the optical density at 490 nm (OD) for each individual (○) and as the median for each group (horizontal line).