FIG. 2.

Bacteremia in mice infected with wild-type FAM20 or the lpxA mutant. Mice were infected with the wild-type bacterial strain FAM20 at 1 × 10⁸ CFU or equivalent amounts of biological material of the lpxA mutant, and bacterial blood titers were monitored. All mice had similar bacteremia levels following infection with the lpxA mutant, except at 24 h postinfection (P < 0.05); however, bacteremia was significantly enhanced in MyD88^−/− mice following infection with the wild-type bacterial strain FAM20 (P < 0.05) at 8, 24, and 72 h postinfection. The counts were analyzed by the nonparametric Mann-Whitney test. N.S., nonsignificant difference.