TABLE 1.

Partial list of genes differentially expressed in I/St and A/Sn macrophages^a

Gene	Score (d) forb:		Protein or genee	Accession no.	Gene name
	Control cellsc	Infected cellsd
Chemokine and cytokine genes
Scyb14f	10.4	5.3	Cxcl14, macrophage inflammatory protein 2 gamma	AW120786	96953_at
Il-11f	9.9	3.4	Interleukin 11	U03421	92266_at
Scyb13f	7.4	6.1	Cxcl13, B-cell homing chemokine	AF030636	102025_at
Ccr5	NS	2.4	Chemokine (C-C motif) receptor 5	AF022990	161968_f_at
Scya11	3.6	NS	Small chemokine (C-C motif) ligand 11 (eotaxin-1)	U77462	92742_at
Il-6f	3.5	NS	Interleukin 6	X54542	102218_at
Scyb2 MIP-2a	3.2	NS	Cxcl-2, macrophage inflammatory protein 2 alpha	X53798	101160_at
Scyb1 MIP-2	2.8	NS	Cxcl-1, macrophage inflammatory protein 2	L12030	95349_g_at
Il-17	−5.6	NS	Interleukin 17	U35108	99349_at
Scyb10	−3.0	NS	Cxcl-10, macrophage interferon-activated protein 10 (IP-10)	M33266	93858_at
Scyb9	−2.9	NS	Cxcl-9, monokine induced by gamma interferon (Mig)	M34815	101436_at
Immune response genes
Ifi205	7.7	3.0	Interferon-activated gene 205	M74123	94224_s_at
Ifi202a	5.3	2.0	Interferon-activated gene 202A	AV229143	94774_at
Saa3f	5.0	3.5	Serum amyloid A 3	X03505	102712_at
Gbp2	−4.8	−2.0	Guanylate nucleotide binding protein 2	AJ007970	104597_at
Chi3l3	NS	3.9	Chitinase 3-like 3	M94584	92694_at
Gbp1	−5.1	NS	Guanylate nucleotide binding protein 1	M55544	95974_at
Psmb9	−4.8	NS	Proteosome (prosome macropain) subunit beta type 9	D44456	93085_at
Ifit2	−4.4	NS	Interferon-induced protein with tetratricopeptide repeats 2	U43085	103639_at
Mx2	−4.2	NS	Myxovirus (influenza virus) resistance 2	J03368	102699_at
Gbp3	−3.4	NS	Guanylate nucleotide binding protein 3	AW047476	103202_at
Mx1	−3.4	NS	Myxovirus (influenza virus) resistance 1	M21038	98417_at
Ifi47	−3.2	NS	Gamma interferon-inducible protein	M63630	104750_at
Cytoskeletal/extracellular matrix genes
Mglap	3.9	2.4	Matrix gamma-carboxyglutamate (gla) protein	D00613	93866_s_at
Csrp1	NS	2.9	Cysteine-rich protein 1	D88793	92608_at
Adam8	NS	2.7	A disintegrin and metalloprotease domain 8	X13335	103024_at
Coro1a	NS	2.1	Coronin actin binding protein 1A	AW122039	96648_at
Mmp8f	NS	−2.4	Matrix metalloproteinase 8	U96696	94769_at
Cldn4	3.2	NS	Claudin 4	AB000713	101410_at
Receptor/cell surface genes
Fpr1	5.2	2.3	Formyl peptide receptor 1	L22181	99387_at
Tm7sf1	−6.7	−7.0	Transmembrane 7 superfamily member 1	AI060729	103017_at
Marco	−5.1	−2.1	Macrophage receptor with collagenous structure	U18424	102974_at
Cd22	−5.0	−3.0	CD22 antigen	L02844	102939_s_at
Il-7r	−3.6	−5.5	Interleukin 7 receptor	M29697	99030_at
Il1rl1	NS	−2.5	Interleukin 1 receptor-like 1	Y07519	98501_at
Taa1	7.8	NS	Tumor-associated antigen 1	U35836	94643_at
Tnfrsf9	4.6	NS	Tumor necrosis factor receptor superfamily member 9	AA798611	103509_at
Bdkrb	3.6	NS	Bradykinin receptor beta	L26047	101748_at
Raet1c	3.3	NS	Retinoic acid early transcript gamma	D64162	102649_s_at
Pira1	3.1	NS	Paired-immunoglobulin-like receptor A1	U96682	95784_at
Ly6a	−4.3	NS	Lymphocyte antigen 6 complex locus A	X04653	93078_at
Itpr5	−3.2	NS	Inositol 145-triphosphate receptor 5	AF031127	101441_i_at
Ifngr	−3.2	NS	Gamma interferon receptor	M28233	99334_at
Csf2rb1	−3.0	NS	Colony-stimulating factor 2 receptor beta 1	M34397	94748_g_at

^aExpression levels of genes in I/St macrophages are given relative to A/Sn macrophages, with negative numbers indicating that the gene is expressed at a higher level in A/Sn macrophages.

^bNS, not significant.

^cRelative interstrain difference in gene expression in uninfected macrophages.

^dRelative interstrain difference in gene expression in infected macrophages.

^eProtein name abbreviation is given in case it differs from the gene name.

^fResults for these genes were confirmed by quantitative real-time assay.