Table 1.
Time constants (τ, in seconds) for changes in clamp current (IC), integrated IC (QC), and volume (VT) of oocytes expressing rSGLT1 and hSGLT1
| rSGLT1 | hSGLT1 | |||
|---|---|---|---|---|
| α-MDG | Arbutin | α-MDG | Arbutin | |
| τ (IC) | 5.5 ± 0.3 (18) | 9.1 ± 0.6 (15) | 8.9 ± 0.5 (16) | 11.1 ± 0.7 (7) |
| τ (QC) | 4.4 ± 0.1 (18) | 8.1 ± 0.6 (15) | 8.8 ± 0.5 (16) | 10.1 ± 0.4 (7) |
| τ (VT) | 4.4 ± 0.3 (18) | 6.3 ± 0.4 (15)* | 8.0 ± 1.2 (16) | 9.0 ± 1.5 (7) |
The time constants of QC and VT were taken as the intercept between the abscissa and the respective regression lines defining the first 40 s of linear change. Zero time was taken as the onset of IC.
*
This value of τ (VT) was significantly smaller than the corresponding values of τ (QC) and τ (IC); P < 0.03.