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. Author manuscript; available in PMC: 2006 Jun 20.
Published in final edited form as: Circ Res. 2005 Oct 13;97(11):1190–1197. doi: 10.1161/01.RES.0000190634.60042.cb

Figure 1.

Figure 1

Feeding and D-4F Treatment Protocol. (A) Time-dependent study. Ldlr −/− mice were divided into 4 groups. Group I received WD alone for 6 weeks. In addition to WD, groups II, III and IV received D-4F in their drinking water for the weeks indicated. (B) Pre-existing disease study. Ldlr −/− mice were divided into 3 groups, Group V received WD alone for 4 weeks while group VI was fed WD for 6 weeks with D-4F in their drinking water after 4 weeks on WD. Group VII was fed lab chow diet for 6 weeks.