Fig. 3.
Effects of ΔE mutation on IFN-γ (Th1 cytokine) secretion. The ΔE mutation in Foxp3 impairs Foxp3-induced inhibition of CD4 T cells cultured alone (A) or with either purified CD4+CD25− T cells (B) or Th1 differentiated CD4 T cells (C).
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