Temporal expression profiles of Per1 (a), Per2 (b), Cry1 (c), Cry2 (d), Clock (e), and Bmal1 (f) in rd mouse retinas under LD (●) and DD (○) conditions. Data are presented as means ± SEM from five mice and expressed as a percentage of the maximum mean expression. Points at ZT/CT [2] are duplicates of ZT/CT 2 replotted to show 24-h trends. One-way ANOVA revealed P < 0.001 for Per1 and Per2 under both LD and DD conditions, P < 0.01 for Cry1 and Bmal1 under both LD and DD conditions, P < 0.05 for Cry2/LD, and P < 0.001 for Cry2/DD. For Per1, Per2, Cry1, Cry2, and Bmal1 expression, the peak-trough amplitudes under LD conditions were 1.65-, 2.54-, 1.46-, 1.35-, and 1.39-fold, respectively, whereas, under DD conditions, they were 1.84-, 2.95-, 1.50-, 1.73-, and 1.26-fold, respectively.