Table 2.

ORs for relationships between OGG1 expression and skin hyperkeratosis.

	Skin hyperkeratosis
OGG1 expression	Absent	Present	OR (95% CI)a	p-Value	Trend p-value
All subjects
0.38–1.17	56	18	1.00 (reference)
1.17–1.53	54	21	1.33 (0.61–2.88)	0.470
1.54–2.01	47	28	2.21 (1.03–4.75)	0.037	0.054b
2.02–4.37	50	24	1.69 (0.78–3.66)	0.180	0.099c
Maled
0.38–1.17	32	9	1.00 (reference)
1.17–1.53	33	9	1.06 (0.35–3.20)	0.92
1.54–2.01	22	13	2.73 (0.92–8.10)	0.071	0.08
2.02–4.37	20	15	2.98 (1.02–8.75)	0.047	0.02
Female
0.38–1.17	24	9	1.00 (reference)
1.17–1.53	21	12	1.71 (0.57 –5.15)	0.34
1.54–2.01	25	15	1.83 (0.60–5.59)	0.29	0.22
2.02–4.37	30	9	0.95 (0.30–3.01)	0.93	0.92

^aData shown are OR (95% CI) adjusted for sex, age, smoking, alcohol use, and pesticide use.

^bp-Value for trend across first three quartiles of OGG1 groups by Wald test.

^cp-Value for trend across all four quartile categories by Wald test.

^dSkin hyperkeratosis status was not ascertained for one male subject.