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. 2006 Feb 9;114(6):842–847. doi: 10.1289/ehp.8781

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Effects of TCE and its metabolites on embryo survival and cushion development. Embryos were treated with PBS or with 4 nmol/egg of TCE, TCA, or TCOH during cushion development. (A) Mean embryo survival ± SE at HH30 (n = 3 experiments; values represent 32 embryos for PBS, 46 for TCE, 41 for TCOH, and 34 for TCA). (B and C) Mean cardiac cushion proliferative index ± SE in OFT (B) and AVC (C), assessed at HH24 using BrdU incorporation. (D and E) Mean cushion cellularity of the OFT (D) and AVC (E). Experiments in B–E were performed in duplicate and represent 7 embryos for PBS, 7 for TCE, 5 for TCOH, and 7 for TCA.

*Significantly different from PBS treatment; p-values are given above bars.