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. 2006 Feb 9;114(6):842–847. doi: 10.1289/ehp.8781

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Effects of TCE on cardiovascular function at HH24. Embryos were treated with PBS or 4 nmol TCE during cushion development. Heart rate (A) and mean dorsal aortic and atrioventricular (both passive and active components for the atrioventricular) blood flow (B) for PBS- and TCE-exposed embryos; values are mean ± SE for 8 PBS or 11 TCE embryos. (C–F) Representative dorsal aortic (C and D) and atrioventricular (E and F) velocity analog waveforms for a PBS-treated (C and E) and a TCE-treated (D and F) embryo; TCE exposure reduced both the dorsal aortic and active atrioventricular velocities. (G and H) Ratio of passive to active atrioventricular blood flow (G) and stroke volume index (H) for PBS- and TCE-exposed embryos.

*Significantly different from PBS treatment; p-values are given above bars.