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. 2006 Jun 27;4(7):e225. doi: 10.1371/journal.pbio.0040225

Figure 7. A Model for CESN Formation.

Figure 7

The tail epidermis derives from the posterior animal b4.2 blastomeres. At the 32-cell stage, FGF9/16/20 induces Nodal and dorsal midline identity in the b6.5 blastomere. At the mid-gastrula stages, ADMP induces ventral midline fate in the overlying epidermis. These first inductive processes lead to a medio-laterally patterned epidermis comprising eight rows of cells in cross section. Finally, Notch signalling controls the number of CESNs in the midline through lateral inhibition.