Figure 4.

Gene Ontology predictions for previously un-annotated ORFs in yeast. (A) Trade-off between anticipated conservative precision and sensitivity. The anticipated conservative precision (y-axis) and the expected number of previously un-annotated ORFs with predictions (x-axis) are plotted by modulating parameters such as k (see Methods). (B) Normal predictions for previously un-annotated ORFs are shown for 31 subcategories for which validations indicate a conservative precision of ≥ 0.3. The subcategories (vertical axis) were sorted by descending number of predictions for conservative precision is larger than 0.3. The colour map reflects the conservative precision of predictions made in each GO subcategory. Red indicates more reliable predictions, yellow represents less reliable predictions. The number in parentheses indicates the total number of predictions made in each subcategory.