Table 2.

Postoperative pain scores and pain related limitation of activity^*

Time	Mean (SD), open surgery	Mean (SD), endoscopic surgery	Difference between the two groups
			Difference in means (95% CI)†	P value	Change over time‡mean (95% CI)	P value
3 weeks	60.5 (23)	52.1 (23)	8.6 (1.0 to 16.3)	0.028	Reference
6 weeks	51.3 (23)	43.3 (23)	8.7 (1.0 to 16.4)	0.030	-0.8 (-9.3 to 7.8)	0.86
3 months	36.2 (20)	23.5 (26)	13.3 (5.3 to 21.3)	0.001	4.2 (-4.3 to 12.7)	0.33
12 months	13.9 (22)	8.7 (21)	5.8 (1.7 to 13.3)	0.13	-3.3 (-11.8 to 5.2)	0.45

^*Score range from 0 (no pain or tenderness in scar or proximal palm and no activity limitation) to 100 (severe pain in scar or proximal palm and severe activity limitation because of pain or tenderness).

^†Analysis of covariance adjusting for baseline characteristics.

^‡Mixed model analysis for difference between open and endoscopic groups in change over time (follow-up score minus baseline score) adjusting for baseline characteristics.