Table 3.
Intention to treat analysis. Hazard ratios of effect of perioperative β blockade on secondary outcomes among patients with diabetes undergoing non-cardiac surgery
| Hazard ratio*(95% CI) | P value | |
|---|---|---|
|
Univariate analyses |
||
| All cause mortality |
1.03 (0.74 to 1.42) |
0.88 |
| Cardiac events |
1.02 (0.67 to 1.57) |
0.91 |
| Cardiac death |
0.85 (0.45 to 1.60) |
0.61 |
| Non-fatal cardiac events |
1.24 (0.70 to 2.17) |
0.46 |
| Non-cardiac death |
1.10 (0.75 to 1.61) |
0.63 |
|
Multivariate analyses |
||
| All cause mortality |
1.01 (0.72 to 1.41) |
0.79 |
| Cardiac events |
1.03 (0.69 to 1.54) |
0.87 |
| Cardiac death |
0.84 (0.46 to 1.52) |
0.56 |
| Non-fatal cardiac events |
1.23 (0.68 to 2.23) |
0.44 |
| Non-cardiac death | 1.13 (0.75 to 1.70) | 0.65 |
Adjusted in multivariate analysis for all variables used for stratification at randomisation and trial drug as mandatory covariates.