Table 1.

Average folding times and thermodynamic transition temperatures

Tether point	Height	Tc	Tf	τave
				T = Tf	T = 0.480
Bulk	N/A	0.600	0.523	3,383 ± 127	2,729 ± 93
1	σ	0.583	0.488	9,536 ± 309	9,022 ± 209
11	σ	0.600	0.557	3,768 ± 152	2,657 ± 101
22	σ	0.625	0.514	3,227 ± 130	2,829 ± 110
34	σ	0.591	0.591	6,154 ± 289	3,232 ± 146
46	σ	0.600	0.523	5,562 ± 214	5,313 ± 209

Average folding times and transition temperatures for the bulk protein and for tether points 1, 11, 22, 34, and 46. τ_ave = (1/M) ${\Sigma }_{\mathrm{i=1}}^M$ τ_1i, and τ_1i is the first passage time to the native state (χ ≥ 0.9) for the ith folding trajectory. All times are reported in units of τ, and all temperatures are given in units of ε_h/k_B. Error estimates are given by σ/$\sqrt{N}$ (25), where σ² = 〈τ²〉 − 〈τ〉² and N = 400, the total number of folding times.