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Selected functional categories of mutated genes in the 96-month isolate from patient 1
| Functional category | No. of genes mutated |
|---|---|
| Virulence factors, virulence regulators | 13 |
| Small-molecule transport, antibiotic resistance | 12 |
| Iron acquisition | 5 |
| DNA replication, cell division, transcription, translation | 5 |
| Quorum sensing | 3 |
| Fatty-acid metabolism | 3 |
| DNA mismatch repair | 1 |
| Anaerobic metabolism | 1 |
