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Effects of intracranial mecamylamine and scopolamine injected into the subregions shown in Fig. 2 on the systemic nicotine- and donepezil-induced blocking effects on reinstatement (n = 7–14). Open squares, open circles, and filled circles represent groups given nonstimuli, MAP-associated cues, and MAP-priming injections, respectively. ∗∗∗, P < 0.001 compared with nicotine- or donepezil-pretreated groups given the cue and MAP priming.
