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. 2006 Jun 5;103(24):8928–8933. doi: 10.1073/pnas.0601687103

Table 3.

CDC reaction of tetrahydroisoquinoline with malononitrileInline graphic

Entry 9, eq TBHP, eq Yield of 10, %* Yield of 11, %*
1 1 1 eq 29 7
2 6 1 eq 46 6
3 1 2 eq 0 36

Tetrahydroisoquinoline (0.1 mmol) was used.

*Isolated yields were based on tetrahydroisoquinoline.