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CtBP mediates the hypoxia-induced migration of H1299 lung cancer cells. (A) H1299 cells grown for 20 h in 20% O2 (Control) or 1% O2 (Hypoxia) were assayed for their migration onto the matrix deposited by cells scraped away at the beginning of the assay. The starting lines for the migration and CtBP siRNA treatment (siCtBP) are indicated. (B) Western blot showing CtBP knockdown in H1299 cells by siRNA treatment.
