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Inhibition of NF-κB activation with adenovirus expressing a stable form of IκB restores sensitivity to inducers of apoptosis. The effect of Adv-IκB-dn or Adv-β-gal on induction of apoptosis by γ-irradiation, etoposide, or TNF-α were examined in Tax transgenic SC (A) and F8 (B) cells, using annexin V and PI staining and FACS analysis.
