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. 2006 Jun 5;103(24):9232–9237. doi: 10.1073/pnas.0602956103

Fig. 3.

Fig. 3.

ArKO−/− mice are predisposed to STZ-induced insulin-deficient diabetes. Cumulative incidence of diabetes (random-fed blood glucose >250 mg/dl) was calculated by Kaplan–Meier estimation in female (A) (n = 10–28) and male (D) (n = 10–30) mice after STZ challenge (150 mg/kg of body weight). (B and E) Random-fed blood glucose (day 8), in female (B) and male (E) mice. (C and F) The ratio of random-fed of insulin (pg/ml) and glucose (mg/dl) at day 8 was used as an index of insulin deficiency in female (C) and male (F) mice. ∗, P < 0.05; ∗∗, P < 0.01.