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. 2006 Jun 5;103(24):9333–9338. doi: 10.1073/pnas.0600905103

Fig. 5.

Fig. 5.

Drug-induced CPP in WT and DAT-CI mice. CPP is represented by the time difference (in seconds) between pre- and postconditioning (mean ± SEM) that mice spend in the drug-paired chamber (n = 8–15). (A) Five and 20 mg/kg cocaine produced significant CPP in WT mice but not in DAT-CI mice compared with saline mice (for genotype difference, F1,66 = 49.96 and P < 0.0001; for genotype × drug interaction, F2,66 = 16.7 and P < 0.0001). (B) AMPH (2.5 mg/kg) produced CPP in both WT and DAT-CI mice (for drug effect, F1,47 = 18.86 and P < 0.0001). ∗, P < 0.05; ∗∗, P < 0.01; ∗∗∗, P < 0.001 between drug and saline in the same genotype; n = 8–15.