Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Jun 2;103(24):9357–9362. doi: 10.1073/pnas.0603161103

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2006 by The National Academy of Sciences of the USA

PMC Copyright notice

Fig. 1. — Identification of genes involved in store-operated calcium entry. (A) The effect of individual gene silencing on TG-evoked Ca²⁺ entry (CCE) relative to basal Ca²⁺, displayed as a histogram. (Inset) The distribution of averaged CCE/basal values for each well. Low values of CCE/basal are enlarged to show the tail of the distribution, representing amplicons that dramatically suppressed TG-evoked calcium entry. (B) The top 10 hits with strongest effect on TG-evoked Ca²⁺ influx. Averaged values of CCE/basal are shown for all 48,384 wells tested in the assay (“mean”), for the top 10 hits from the screen, and for the positive control well that contained Stim dsRNA in each assay plate (“Stim Ave”). Striped bars represent hits with transmembrane regions. (C) Transmembrane (TM) protein hits.