Table 3.
Comparison of the PQIs (Kruskal-Wallis Rank Sum Tests). See Additional files 2, Additional files 3, Additional files 4, Additional files 5, Additional files 6, Additional files 7 and 8 for the corresponding boxplots.
| Null hypotheses† | ||||||
| GOAPUB ≠ GOA | GOAPUB ≠ PUB | +Dep. ≠ +Random | ||||
| Clusters | χ2 | p-value‡ | χ2 | p-value‡ | χ2 | p-value‡ |
| Iron metabolism: | ||||||
| Down | 48.9203 | *** | 41.2014 | *** | 255.7346 | *** |
| Up | 27.1614 | *** | 41.1756 | *** | 73.0033 | *** |
| Glioblastomas: | ||||||
| glioGBM | 29.7468 | *** | 1.1743 | ns | 85.9769 | *** |
| glioPRIM | 62.7100 | *** | 90.2077 | *** | 97.2004 | *** |
| glioSEC | 0.6282 | ns | 1.5421 | ns | 76.2122 | *** |
| Circadian Rhythms: | ||||||
| circ | 53.1073 | *** | 26.2437 | *** | 126.8363 | *** |
| Human fetal lung: | ||||||
| lung | 19.0615 | *** | 36.1988 | *** | 16.3595 | *** |
| Human retinal pigment epithelium: | ||||||
| arpe19 | 3.999 | * | 9.5254 | * | 42.7507 | *** |
| rpe | 21.2666 | *** | 30.0108 | *** | 105.1405 | *** |
| Alzeimers disease: | ||||||
| alzheimer | 121.7634 | *** | 151.0647 | *** | 14.2819 | *** |
| Acute lymphoblastic leukemias: | ||||||
| bcr-abl | 41.6444 | *** | 44.5055 | *** | 137.2054 | *** |
| hyperdiploid | 14.0618 | *** | 22.3200 | *** | 137.0784 | *** |
| novel | 21.1505 | *** | 91.1497 | *** | 22.9347 | *** |
| tel-aml1 | 15.5670 | *** | 6.5539 | ns | 118.602 | *** |
† Null hypotheses: comparison of the PQIs between Evidence (GOA) and a combination of Evidence and Literature (GOAPUB ≠ GOA). Comparison of the PQIs between Literature (PUB) and a combination of Evidence and Literature (GOAPUB ≠ PUB). Comparison of the PQIs between the combination of Evidence and Literature enriched with the associative relations (+Dep.) or a random term set of the same size (+Random).
‡ p-value: ≤ 0.01 (***) ; ≤ 0.05 (*) ; non-significant (ns).