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. Author manuscript; available in PMC: 2006 Jun 23.
Published in final edited form as: Neuron Glia Biol. 2004 Feb;1(1):47–55. doi: 10.1017/S1740925X04000079

Fig. 3.

Fig. 3

Remyelination after transplantation of hPAP-OECs into an X–EB dorsal funiculus lesion. (A) Low-power, plastic-embedded section of the dorsal spinal cord 3 weeks after hPAP-OEC transplantation. (B) A higher power micrograph shows extensive myelinated profiles throughout the transplantation site. (C) In adjacent, frozen sections reacted for ALP, blue reaction product can be observed in the transplantation site. (D) Higher power of this area shows numerous blue profiles that are characteristic of myelinated axons and similar to that observed following SC transplantation (Fig. 2). (E) Higher power images of plastic-embedded sections shows myelinated axons, many of which are associated with large cytoplasmic and nuclear surrounds characteristic of peripheral myelination. (F) These profiles are associated with hPAP reaction product. Scale bar: 200 μm in A,C; 25 μm in B,D; 7 μm in E,F.