Table 1. Relative NO-producing activities of NOS in various cellular compartments.
NOS isoform | Subcellular location | Activity | Reference(s) |
---|---|---|---|
eNOS | PM | High | [42,49,90] |
eNOS | Cytosol | Low | [5,115] |
eNOS | Golgi (cis) | Moderate | [49] |
eNOS | Golgi (trans) | Low | [49] |
eNOS | Nucleus | Very low | [50] |
eNOS | Mitochondrion | Low | [50] |
eNOS | Cytoskeleton (actin) | Low | [43,44] |
eNOS | Cytoskeleton (tubulin) | High | [51] |
iNOS | Peroxisome | Unknown | [61] |
iNOS | PM | High | [50] |
iNOS | Nucleus | High | [50] |
iNOS | Mitochondrion | High | [50] |