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Effect on plasmid stability of replacement of the δ promoter (Pδ) with the copS promoter (copSp) or ω promoter (Pω). •, pUSE2 vector; ▪, pUSE1000 carrying the δ and ω genes; ▴, pUSE3000 carrying the copS promoter (PcopS) upstream of the δ gene; ⧫, pUSE7000 carrying the ω promoter (Pω) upstream of the δ gene. The plasmid loss rate per generation is indicated next to the appropriate curve on the graph.
