Table 1.

Tumorigenicity of MPM cell lines after orthotopic and subcutaneous implantation in nude mice.

Cell line	Histology	Tumorigenicity	Implantation method	Survival(days) (mean ± SD)	Survival (days) (Min/Max)
IST-Mes2	Epithelioid	0/15	Orthotopic	-	-
	Epithelioid	0/15	Subcutaneous	-	-
IST-Mes3	Biphasic	15/15	Orthotopic	81,5 ± 21,7	60/122
	Biphasic	15/15	Subcutaneous	Sacrificed after 90 days	-
IST-Mes3/2P	Biphasic	15/15	Orthotopic	69,6 ± 14,5	54/89
MM-B1	Biphasic	15/15	Orthotopic	72,5 ± 6,4	68/77
	Biphasic	0/15	Subcutaneous	-	-

2 × 10⁶ MPM cells were injected into the pleural cavity of nude mice. The experiment ended when mice were moribund.