Table 4.
Growth progression of MM-B1 cell line after orthotopic implantation in nude mice.
| Days after implantation | 38 | 45 | 52 | 59 | 66 | 73 |
| Mediastinum nodules | < 101 | 10–201 | 10–202 | 10–202 | >203 | >203 |
| Pericardium nodules | < 101 | 10–201 | 10–202 | 10–202 | >203 | >203 |
| Parietal Pleura nodules | - | - | - | 10–202 | >203 | >203 |
| Lungs nodules | - | - | - | 10–202 | >203 | >203 |
| Diaphragms nodules | - | - | - | - | - | - |
2 × 106 MM-B1 cells were injected into the pleural cavity of nude mice. At indicated times, mice were sacrificed and tumor nodules were counted, measured, removed and frozen for immunohistochemical analysis. Data shown are mean of 5 mice.
1 Nodule diameter ≤ 1 mm; 2 Nodule diameter 2–3 mm; 3 Nodule diameter ≥ 3 mm. No nodules were found before the days indicated in the table.